The role of hospital chief financial officer has changed dramatically over the last 50 years. No longer simply responsible for managing the hospital’s finances, today’s CFO is a change agent, an indispensable member of the leadership team helping chart his or her organization’s long-term success. This white paper examines how the role of hospital CFO has evolved, some ways in which CFOs act as change agents, and how CFOs can draw on their financial expertise and leadership skills to become change-makers in their organizations.